This is actually sort of silly, but I don’t feel very well (I am recovering from Cruise Crud quite nicely, but it’s slow), and it made me laugh.
The phrase “bunch of loons” refers to anyone who is critical of Nicole’s fabulous lifestyle. One of “us” is equivalent to Israel Keyes.
And who was Israel Keyes? In case you don’t remember, or barely remember:
Israel Keyes was a pretty notorious serial killer who committed suicide in prison.
So “Charles” is saying that “he” thinks that Nicole’s critics are harboring a serial killer. We’re losing our “souls.” (Sorry, Charlie, but I’m an atheist. We don’t have souls the first place.)
“Charles,” however, didn’t really think through “his” analogy.
“Charles” is sort of fixated on serial killers. “He” likes this sort of thing: